Discovery of Novel 3-Phenylpiperidine Derivatives Targeting the β-Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD-1 Antibody for the Treatment of Colorectal Cancer-Reference-Cited by-同舟云学术

Discovery of Novel 3-Phenylpiperidine Derivatives Targeting the β-Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD-1 Antibody for the Treatment of Colorectal Cancer

Published:2023-01-11 Issue:2 Volume:66 Page:1349-1379
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Hao¹²^ORCID,Liu Chenglong¹^ORCID,Chen Qiushi²³,Shen Li-An¹,Xiao Wenting¹²,Li Jiayi²³,Wang Yonghui¹^ORCID,Zhu Di¹⁴,Zhang Qingwei²,Li Jianqi²

Affiliation:

1. School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China

2. Novel Technology Center of Pharmaceutical Chemistry, Shanghai Institute of Pharmaceutical Industry Co., Ltd., China State Institute of Pharmaceutical Industry, 285 Gebai Ni Road, Shanghai 201203, China

3. School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, 333 Longteng Road, Shanghai 201620, China

4. Department of Pharmacology, School of Basic Medical Science, Fudan University, 138 Yixue Yuan Road, Shanghai 201100, China

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

National Science and Technology Major Project

Graduate Innovation Fund Project of China State Institute of Pharmaceutical Industry

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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