Dipeptide-Derived Alkynes as Potent and Selective Irreversible Inhibitors of Cysteine Cathepsins-Reference-Cited by-同舟云学术

Dipeptide-Derived Alkynes as Potent and Selective Irreversible Inhibitors of Cysteine Cathepsins

Published:2023-03-03 Issue:6 Volume:66 Page:3818-3851
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Behring Lydia¹²,Ruiz-Gómez Gloria³,Trapp Christian¹,Morales Maryann¹,Wodtke Robert¹^ORCID,Köckerling Martin⁴^ORCID,Kopka Klaus¹²,Pisabarro M. Teresa³^ORCID,Pietzsch Jens¹²^ORCID,Löser Reik¹²

Affiliation:

1. Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, 01328 Dresden, Germany

2. Technische Universität Dresden, School of Science, Faculty of Chemistry and Food Chemistry, Mommsenstraße 4, 01069 Dresden, Germany

3. BIOTEC, Technische Universität Dresden, Tatzberg 47-51, 01307 Dresden, Germany

4. Institute of Chemistry, University of Rostock, Albert-Einstein-Straße 3a, 18059 Rostock, Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01360

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