Inducible Degradation of Oncogenic Nucleolin Using an Aptamer-Based PROTAC-Reference-Cited by-同舟云学术

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Inducible Degradation of Oncogenic Nucleolin Using an Aptamer-Based PROTAC

Published:2023-01-06 Issue:2 Volume:66 Page:1339-1348
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Miao¹,Zhou Ping²,Kong Yun²,Li Jingrui¹,Li Yan²,Zhang Yao²,Ran Jie²,Zhou Jun²³,Chen Yan²,Xie Songbo¹²^ORCID

Affiliation:

1. School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China

2. Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan 250014, China

3. College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01557

Reference47 articles.

1. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

2. Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery

3. Transforming targeted cancer therapy with PROTACs: A forward-looking perspective

4. Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

5. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4

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1. Engineering artificial non-coding RNAs for targeted protein degradation;Nature Chemical Biology;2024-08-30

2. Targeted degradation of membrane and extracellular proteins with LYTACs;Acta Pharmacologica Sinica;2024-08-05

3. PROTAC: Novel degradable approach for different targets to treat breast cancer;European Journal of Pharmaceutical Sciences;2024-07

4. Repurposing AS1411 for constructing ANM-PROTACs;Cell Chemical Biology;2024-07

5. An engineered DNA aptamer-based PROTAC for precise therapy of p53-R175H hotspot mutant-driven cancer;Science Bulletin;2024-07

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