Dynamic Intramolecular Cap for Preserving Metallodrug Integrity─A Case of Catalytic Fluoroquinolones
Author:
Affiliation:
1. Edith and Joseph Fischer Enzyme Inhibitors Laboratory, Schulich Faculty of Chemistry, Technion─Israel Institute of Technology, Haifa3200003, Israel
Funder
Ministry of Industry, Trade and Labor
Israel Science Foundation
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01302
Reference59 articles.
1. World Health Organization. Antimicrobial resistance. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance.
2. Antibiotic resistance threats in the United States, 2019
3. Jim, O’Neill. Tackling Drug-Resistant Infections Globally: Final Report and Recommendations; 2016.
4. Pharmacokinetics and Pharmacodynamics of Fluoroquinolones
5. Mechanism of Quinolone Action and Resistance
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