Hematopoietic Progenitor Kinase 1 in Tumor Immunology: A Medicinal Chemistry Perspective-Reference-Cited by-同舟云学术

Hematopoietic Progenitor Kinase 1 in Tumor Immunology: A Medicinal Chemistry Perspective

Published:2022-06-13 Issue:12 Volume:65 Page:8065-8090
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhu Qiangsheng¹,Chen Nannan¹,Tian Xinjian¹,Zhou Yeling¹,You QiDong¹^ORCID,Xu Xiaoli¹^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines and Jiang Su Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China

Funder

State Key Laboratory of Natural Medicines

Qinglan Project of Jiangsu Province of China

China Pharmaceutical University

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Double First Class Innovation Team and Original exploration project

Foundation Research Project of Jiangsu Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00172

Reference147 articles.

1. Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade.

2. HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway.

3. Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated protein kinase

4. Involvement of Hematopoietic Progenitor Kinase 1 in T Cell Receptor Signaling

5. Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell–mediated immune responses

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