New Generation of sGC Stimulators: Discovery of Imidazo[1,2-<i>a</i>]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension-Reference-Cited by-同舟云学术

New Generation of sGC Stimulators: Discovery of Imidazo[1,2-a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension

Published:2023-04-11 Issue:11 Volume:66 Page:7280-7303
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vakalopoulos Alexandros¹^ORCID,Wunder Frank¹,Hartung Ingo V.¹^ORCID,Redlich Gorden¹,Jautelat Rolf¹,Buchgraber Philipp¹,Hassfeld Jorma¹,Gromov Alexey V.¹,Lindner Niels¹,Bierer Donald¹,Gries Jörg¹,Kroh Walter¹,Paulsen Holger¹,Mittendorf Joachim¹,Lang Dieter¹^ORCID,Becker-Pelster Eva¹,Brockschnieder Damian¹,Geiss Volker¹,Li Volkhart¹,Straub Alexander¹,Knorr Andreas¹,Mondritzki Thomas¹²,Trübel Hubert¹²,Raschke Marian¹,Schaefer Martina¹³,Thomas Dirk¹,Sandner Peter¹⁴,Stasch Johannes-Peter¹⁵,Follmann Markus¹^ORCID

Affiliation:

1. Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany

2. University of Witten/Herdecke, 58455 Witten, Germany

3. Lead Discovery, Nuvisan ICB GmbH, Muellerstrasse 178, 13353 Berlin, Germany

4. Department of Pharmacology, Hannover Medical School, 30625 Hannover, Germany

5. Institute of Pharmacy, Martin Luther University, 06120 Halle, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c02082