Development of an Orally Active Small-Molecule Inhibitor of Receptor Activator of Nuclear Factor-κB Ligand

Author:

Yang Kai1,Li Shunyao2,Wang Tianqi1,Yan Xueming1,He Qian2,Ning Ruonan1,Xu Xing1ORCID,Yao Wei3,Zhang Xiaofei2ORCID,Yang Chunhao2ORCID,Jiang Min1,Deng Lianfu1

Affiliation:

1. Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai 200025, China

2. State Key Laboratory of Drug Research, Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China

3. Center for Musculoskeletal Health, Department of Internal Medicine, The University of California at Davis Medical Center, Sacramento, California 95817, United States

Funder

Science and Technology Commission of Shanghai Municipality

State Key Laboratory of Drug Research

Shanghai Talent Development

Shanghai Municipal Health Bureau young scientific research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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