Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential, and Multiacting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer-Reference-Cited by-同舟云学术

Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential, and Multiacting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer

Published:2022-05-25 Issue:11 Volume:65 Page:7993-8010
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Deng Xiangping¹,Xie Baohua²,Li Qiuzi¹,Xiao Yuan²,Hu Zhiye²,Deng Xiaofei²,Fang Pingping³,Dong Chune²,Zhou Hai-Bing²^ORCID,Huang Jian¹

Affiliation:

1. College of Life Sciences, Wuhan University, Bayi Road, Wuhan 430072, China

2. State Key Laboratory of Virology, Frontier Science Center for Immunology and Metabolism, Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, Donghu Road, Wuhan 430071, China

3. Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China

Funder

Ministry of Science and Technology of the People's Republic of China

Central University Basic Research Fund of China

Wuhan University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00525