SAGE-718: A First-in-Class N-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment
Author:
Affiliation:
1. Sage Therapeutics, Inc., 215 First Street, Cambridge, Massachusetts 02142, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00313
Reference27 articles.
1. Breakthroughs in neuroactive steroid drug discovery
2. Allosteric Modalities for Membrane-Bound Receptors: Insights from Drug Hunting for Brain Diseases
3. The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate Receptors
4. Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches To Treat Central Nervous System Disorders
5. Glutamate Receptor Ion Channels: Structure, Regulation, and Function
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