Traversing through the Dynamic Protein–Protein Interaction Landscape and Conformational Plasticity of PD-1 for Small-Molecule Discovery
Author:
Affiliation:
1. Translational Health Science and Technology Institute (THSTI), Haryana 121001, India
2. Delhi Pharmaceutical Sciences and Research University (DPSRU), Delhi 110017, India
Funder
Council of Scientific and Industrial Research, India
Department of Biotechnology , Ministry of Science and Technology
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00176
Reference84 articles.
1. New immunotherapies targeting the PD-1 pathway
2. The blockade of immune checkpoints in cancer immunotherapy
3. Regulation of PD-L1: Emerging Routes for Targeting Tumor Immune Evasion
4. Mechanistic overview of immune checkpoints to support the rational design of their combinations in cancer immunotherapy
5. Immunomodulators targeting the PD-1/PD-L1 protein-protein interaction: From antibodies to small molecules
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Identification and structural characterization of a pathogenic ARSA missense variant in two consanguineous families from Jammu and Kashmir (India) with late infantile metachromatic leukodystrophy;Molecular Biology Reports;2023-12-28
2. Harnessing the druggability at orthosteric and allosteric sites of PD-1 for small molecule discovery by an integrated in silico pipeline;Computational Biology and Chemistry;2023-12
3. Advances in the structural characterization of complexes of therapeutic antibodies with PD-1 or PD-L1;mAbs;2023-08-02
4. Targeting protein-protein interactions with low molecular weight and short peptide modulators: insights on disease pathways and starting points for drug discovery;Expert Opinion on Drug Discovery;2023-05-29
5. SARS-CoV-2 envelope protein attain K ac mediated dynamical interaction network to adopt ‘histone mimic’ at BRD4 interface;Journal of Biomolecular Structure and Dynamics;2023-03-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3