Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators

Published:2022-04-20 Issue:8 Volume:65 Page:6338-6351
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Clark Jennifer M.¹,Salgado-Polo Fernando²,Macdonald Simon J. F.³^ORCID,Barrett Tim N.³^ORCID,Perrakis Anastassis²^ORCID,Jamieson Craig¹^ORCID

Affiliation:

1. Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom

2. Oncode Institute and Division of Biochemistry, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands

3. Medicines Design, GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom

Funder

Medical Research Scotland

GlaxoSmithKline

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00368

Reference43 articles.

1. Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity

2. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

3. Autotaxin: structure-function and signaling

4. Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions

5. Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: A focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of two novel chemical classes of Autotaxin (ATX) inhibitors using Enalos Asclepios KNIME nodes;Bioorganic & Medicinal Chemistry Letters;2024-05

2. Autotaxin and Lysophosphatidate Signaling: Prime Targets for Mitigating Therapy Resistance in Breast Cancer;World Journal of Oncology;2024-02

3. Experimental autotaxin inhibitors for the treatment of idiopathic pulmonary fibrosis;Expert Opinion on Investigational Drugs;2024-02

4. Virtual screening and molecular dynamics investigations using natural compounds against autotaxin for the treatment of chronic pain;Journal of Biomolecular Structure and Dynamics;2024-01-29

5. Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids;European Journal of Medicinal Chemistry;2024-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3