Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease-Reference-Cited by-同舟云学术

Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease

Published:2022-10-13 Issue:20 Volume:65 Page:13852-13865
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hirose Yuya¹,Shindo Naoya¹^ORCID,Mori Makiko¹,Onitsuka Satsuki¹,Isogai Hikaru¹,Hamada Rui¹,Hiramoto Tadanari¹,Ochi Jinta¹,Takahashi Daisuke¹,Ueda Tadashi¹,Caaveiro Jose M. M.¹^ORCID,Yoshida Yuya¹,Ohdo Shigehiro¹,Matsunaga Naoya¹,Toba Shinsuke²³,Sasaki Michihito²,Orba Yasuko²,Sawa Hirofumi²⁴⁵,Sato Akihiko²³,Kawanishi Eiji¹,Ojida Akio¹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka812-8582, Japan

2. International Institute for Zoonosis Control, Hokkaido University, North 20, West 10 Kita-ku, Sapporo001-0020, Japan

3. Drug Discovery and Disease Research Laboratory, Shionogi & Co. Ltd., 3-1-1 Futaba-cho, Toyonaka, Osaka561-0825, Japan

4. One Health Research Center, Hokkaido University, North 18, West 9 Kita-ku, Sapporo060-0818, Japan

5. Global Virus Network, 725 West Lombard St. Room S413, Baltimore, Maryland21201, United States

Funder

Sumitomo Foundation

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01081

Reference50 articles.

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