Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78-Reference-Cited by-同舟云学术

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Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78

Published:2022-12-14 Issue:1 Volume:66 Page:677-694
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ambrose Andrew J.¹^ORCID,Sivinski Jared¹,Zerio Christopher J.¹^ORCID,Zhu Xiaoyi¹,Godek Jack¹,Kumirov Vlad K.²,Coma Brujas Teresa¹,Torra Garcia Joan¹,Annadurai Anandhan¹,Schmidlin Cody J.¹,Werner Alyssa¹^ORCID,Shi Taoda¹,Zavareh Reza Beheshti³,Lairson Luke³^ORCID,Zhang Donna D.¹,Chapman Eli¹^ORCID

Affiliation:

1. Department of Pharmacology and Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona85721, United States

2. Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona85719, United States

3. Department of Chemistry, The Scripps Research Institute, La Jolla, California92037, United States

Funder

University of Arizona

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01631

Reference53 articles.

1. The Hsp70 chaperone network

2. The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions

3. The HSP70 family and cancer

4. Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP

5. Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins;Biochemistry;2024-01-20

2. Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy;European Journal of Medicinal Chemistry;2023-12

3. Peptide-based molecules for the disruption of bacterial Hsp70 chaperones;Current Opinion in Chemical Biology;2023-10

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