Protein Lysine Methyltransferase SMYD2: A Promising Small Molecule Target for Cancer Therapy-Reference-Cited by-同舟云学术

Protein Lysine Methyltransferase SMYD2: A Promising Small Molecule Target for Cancer Therapy

Published:2022-08-01 Issue:15 Volume:65 Page:10119-10132
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zheng Quan¹,Zhang Wen¹,Rao Guo-Wu¹

Affiliation:

1. College of Pharmaceutical Science, Zhejiang University of Technology, and Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China

Funder

Science and Technology Department of Zhejiang Province

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00325

Reference70 articles.

1. Epigenetic and epitranscriptomic changes in colorectal cancer: Diagnostic, prognostic, and treatment implications

2. Targeting protein lysine methylation and demethylation in cancers

3. Chromatin proteins and modifications as drug targets

4. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis

5. Enhanced SMYD3 expression is essential for the growth of breast cancer cells

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