Long Residence Time at the Vasopressin V2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease-Reference-Cited by-同舟云学术

Long Residence Time at the Vasopressin V₂ Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease

Published:2022-04-01 Issue:11 Volume:65 Page:7717-7728
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Haoran¹,Yan Wenzhong²,Sun Yongzhan³,Yuan Haoxing¹,Su Limin¹,Cao Xudong¹,Wang Peng¹,Xu Zhou¹^ORCID,Hu Youhui¹,Wang Zhongjian¹,Wang Yinan¹,Fu Kequan¹,Sun Ying¹,Chen Yupeng³,Cheng Jianjun²^ORCID,Guo Dong¹^ORCID

Affiliation:

1. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou 221004, Jiangsu, China

2. iHuman Institute, ShanghaiTech University, Shanghai 201210, China

3. The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Institute of Urology, Tianjin Medical University, Tianjin 300070, China

Funder

Natural Science Foundation of Jiangsu Province

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Tianjin Municipal Education Commission

Jiangsu Higher Education Institutions

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00011