Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase-Reference-Cited by-同舟云学术

Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase

Published:2022-10-18 Issue:20 Volume:65 Page:13681-13691
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Beebe Jenny¹,Josephraj Sophia²,Wang Chao J.¹,Danielson Jacob³^ORCID,Cui Qingbin²^ORCID,Huang Caoqinglong²,Barlow Lincoln¹,Zhang Ryan H.³,Zhang Taolan²,Nakshatri Harikrishna⁴,Dong Zizheng²,Li Xiaohong²,Liu Jing-Yuan³,Zhang Jian-Ting²^ORCID

Affiliation:

1. Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

2. Department of Cell & Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614, United States

3. Department of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614, United States

4. Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00642

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