Potent Uncompetitive Inhibitors of Nicotinamide <i>N</i>-Methyltransferase (NNMT) as In Vivo Chemical Probes-Reference-Cited by-同舟云学术

Potent Uncompetitive Inhibitors of Nicotinamide N-Methyltransferase (NNMT) as In Vivo Chemical Probes

Published:2022-10-26 Issue:21 Volume:65 Page:14642-14654
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Barrows Robert D.¹^ORCID,Jeffries Daniel E.¹,Vishe Mahesh¹,Tukachinsky Hanna¹,Zheng Shao-Liang¹^ORCID,Li Fanfan²,Ma Zhenjie²,Li Xiaolei²,Jin Shujuan²,Song Haobin²,Zhang Ruonan²,Zhang Shaofeng²,Ni Jing²,Luan Haofei²,Wen Lei²,Rongshan Yan³,Ying Chen³,Shair Matthew D.¹

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

2. Pharmaron Beijing Co., Ltd., 6 Taihe Road, BDA, Beijing 100176, China

3. WuXi AppTec Co., Ltd., #288 FuTe ZhongLu WaiGaoQiao Free Trade Zone, Shanghai 200131, China

Funder

Sumitomo Dainippon Pharma Oncology

Blavatnik Biomedical Accelerator Fund, Harvard University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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