Discovery and Characterization of PROTACs Targeting Tissue Transglutaminase (TG2)

Author:

Valdivia Andres1,Vagadia Purav P.2,Guo Guangxu3,O’Brien Eilidh1,Matei Daniela145,Schiltz Gary E.246ORCID

Affiliation:

1. Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States

2. Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States

3. WuXi AppTec, Shanghai 200131, People’s Republic of China

4. Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States

5. Jesse Brown VA Medical Center, Chicago, Illinois 60612, United States

6. Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, United States

Funder

Congressionally Directed Medical Research Programs

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. PROTACs in Ovarian Cancer: Current Advancements and Future Perspectives;International Journal of Molecular Sciences;2024-05-07

2. Shaping Oncogenic Microenvironments: Contribution of Fibronectin;Frontiers in Cell and Developmental Biology;2024-04-10

3. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders;European Journal of Medicinal Chemistry;2024-02

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