Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors

Author:

Zhang Shu-Wei12,Gong Chao-Jun1,Su Ming-Bo1,Chen Fei1,He Ting3,Zhang Yang-Ming14,Shen Qian-Qian3,Su Yi3,Ding Jian3,Li Jia1,Chen Yi3,Nan Fa-Jun14ORCID

Affiliation:

1. State Key Laboratory of Drug Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China

2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, P. R. China

3. Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

4. Yantai Key Laboratory of Nanomedicine & Advanced Preparations, Yantai Institute of Materia Medica, Shandong 264000, China

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Ministry of Science and Technology of the People's Republic of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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