Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites-Reference-Cited by-同舟云学术

Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites

Published:2019-02-14 Issue:5 Volume:62 Page:2798-2813
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Krall Jacob¹,Bavo Francesco¹²,Falk-Petersen Christina B.¹,Jensen Claus H.¹,Nielsen Julie O.¹,Tian Yongsong¹,Anglani Valeria¹,Kongstad Kenneth T.¹^ORCID,Piilgaard Louise¹,Nielsen Birgitte¹,Gloriam David E.¹,Kehler Jan³,Jensen Anders A.¹,Harpsøe Kasper¹^ORCID,Wellendorph Petrine¹^ORCID,Frølund Bente¹^ORCID

Affiliation:

1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark

2. Department of Pharmaceutical Sciences, University of Milan, via Mangiagalli 25, 20133 Milano, Italy

3. Discovery Chemistry and DMPK, H. Lundbeck A/S, Ottiliavej, DK-2500 Valby, Denmark

Funder

Lundbeckfonden

Novo Nordisk Fonden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00131

Reference44 articles.