2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes-Reference-Cited by-同舟云学术

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes

Published:2020-02-11 Issue:6 Volume:63 Page:2941-2957
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bhattarai Sanjay¹,Pippel Jan²,Scaletti Emma²,Idris Riham¹,Freundlieb Marianne¹,Rolshoven Georg¹,Renn Christian¹,Lee Sang-Yong¹,Abdelrahman Aliaa¹,Zimmermann Herbert³,El-Tayeb Ali¹,Müller Christa E.¹^ORCID,Sträter Norbert²^ORCID

Affiliation:

1. PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany

2. Institute of Bioanalytical Chemistry, Center for Biotechnology and Biomedicine, Leipzig University, Deutscher Platz 5, D-04103 Leipzig, Germany

3. Institute of Cell Biology and Neuroscience, Goethe-University, D-60438 Frankfurt am Main, Germany

Funder

Deutsche Forschungsgemeinschaft

Ministry for Innovation, Science, Research and Technology of the State of North-Rhine-Westfalia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01611

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