Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir-Reference-Cited by-同舟云学术

Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir

Published:2019-04-02 Issue:7 Volume:62 Page:3553-3574
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

A. M. Subbaiah Murugaiah,Mandlekar Sandhya,Desikan Sridhar,Ramar Thangeswaran,Subramani Lakshumanan,Annadurai Mathiazhagan,Desai Salil D.,Sinha Sarmistha,Jenkins Susan M.,Krystal Mark R.,Subramanian Murali,Sridhar Srikanth,Padmanabhan Shweta,Bhutani Priyadeep,Arla Rambabu,Singh Shashyendra,Sinha Jaydeep,Thakur Megha,Kadow John F.,Meanwell Nicholas A.^ORCID

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00002

Reference70 articles.

1. Current status and prospects of HIV treatment

2. Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada

3. Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends

4. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS

5. Investigational protease inhibitors as antiretroviral therapies

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