Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic-Reference-Cited by-同舟云学术

Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic

Published:2019-11-08 Issue:1 Volume:63 Page:418-424
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ann Jihyae¹,Kim Ho Shin¹,Thorat Shivaji A.¹,Kim Hee²,Ha Hee-Jin²,Choi Kwanghyun²,Kim Young-Ho²,Kim Minseok³,Hwang Sun Wook³,Pearce Larry V.⁴,Esch Timothy E.⁴,Turcios Noe A.⁴,Blumberg Peter M.⁴,Lee Jeewoo¹^ORCID

Affiliation:

1. Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea

2. Medifron DBT, Sandanro 349, Danwon-gu, Ansan-si, Gyeonggi-do 15426, Republic of Korea

3. Department of Biomedical Sciences and Department of Physiology, Korea University College of Medicine, Seoul 02841, Republic of Korea

4. Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-4255, United States

Funder

National Cancer Institute

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01046

Reference34 articles.

1. Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists

2. The capsaicin receptor: a heat-activated ion channel in the pain pathway