Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions
Author:
Affiliation:
1. Infection and Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton Campus, Clayton, VIC 3800, Australia
Funder
Cooperative Research Centres, Australian Government Department of Industry
Monash University
National Health and Medical Research Council
Sir James McNeil Foundation
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00757
Reference80 articles.
1. The aminopeptidase from hog intestinal brush border
2. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin.
3. The moonlighting enzyme CD13: old and new functions to target
4. The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing
5. Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Isolation, synthesis and medicinal chemistry of biphenyl analogs – A review;Results in Chemistry;2023-12
2. Development of Hydroxamate Derivatives Containing a Pyrazoline Moiety as APN Inhibitors to Overcome Angiogenesis;Molecules;2022-11-29
3. De novo design of an ultrasensitive fluorogenic probe for aminopeptidase N sensing in living system;Sensors and Actuators B: Chemical;2022-07
4. Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition;ACS Chemical Biology;2022-06-29
5. Progress and Future Directions with Peptide-Drug Conjugates for Targeted Cancer Therapy;Molecules;2021-10-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3