De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives-Reference-Cited by-同舟云学术

De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives

Published:2019-06-28 Issue:14 Volume:62 Page:6615-6629
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Heim Christopher¹,Pliatsika Dimanthi²,Mousavizadeh Farnoush²,Bär Kerstin¹,Hernandez Alvarez Birte¹,Giannis Athanassios²^ORCID,Hartmann Marcus D.¹^ORCID

Affiliation:

1. Department of Protein Evolution, Max Planck Institute for Developmental Biology, Max-Planck-Ring 5, 72076 Tübingen, Germany

2. Faculty for Chemistry und Mineralogy, Institute of Organic Chemistry, University of Leipzig, Johannisallee 29, 04103 Leipzig, Germany

Funder

Max-Planck-Gesellschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00454

Reference60 articles.

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2. A short history of thalidomide embryopathy

3. Thalidomide-induced limb defects: resolving a 50-year-old puzzle

4. Thalidomide in Low Doses is Effective for the Treatment of Resistant or Relapsed Multiple Myeloma and for Plasma Cell Leukaemia

5. US Thalomid Label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020785s061lbl.pdf (accessed Dec 9, 2018).

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