Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs-Reference-Cited by-同舟云学术

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Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs

Published:2020-01-02 Issue:3 Volume:63 Page:1002-1031
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jeffries Benjamin¹,Wang Zhong¹^ORCID,Felstead Hannah R.¹,Le Questel Jean-Yves²^ORCID,Scott James S.³^ORCID,Chiarparin Elisabetta³^ORCID,Graton Jérôme²^ORCID,Linclau Bruno¹^ORCID

Affiliation:

1. School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.

2. CEISAM UMR CNRS 6230, Faculté des Sciences et des Techniques, Université de Nantes 2, rue de la Houssinière − BP 92208, 44322 Nantes Cedex 3, France

3. Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB40WG, U.K.

Funder

AstraZeneca

Engineering and Physical Sciences Research Council

Centre de Calcul Intensif des Pays de Loire

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01172

Reference102 articles.

1. Applications of Fluorine in Medicinal Chemistry

2. Fluorine in medicinal chemistry

3. The Many Roles for Fluorine in Medicinal Chemistry

4. Fluorine in Medicinal Chemistry

5. Understanding organofluorine chemistry. An introduction to the C–F bond

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