Novel Aryloxyethyl Derivatives of 1-(1-Benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) Phosphorylation-Preferring Serotonin 5-HT1A Receptor-Biased Agonists with Robust Antidepressant-like Activity

Author:

Sniecikowska Joanna1ORCID,Gluch-Lutwin Monika1,Bucki Adam1ORCID,Więckowska Anna1ORCID,Siwek Agata1,Jastrzebska-Wiesek Magdalena1,Partyka Anna1,Wilczyńska Daria1,Pytka Karolina1,Pociecha Krzysztof1,Cios Agnieszka1,Wyska Elżbieta1,Wesołowska Anna1,Pawłowski Maciej1,Varney Mark A.2,Newman-Tancredi Adrian2ORCID,Kolaczkowski Marcin1ORCID

Affiliation:

1. Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland

2. Neurolixis Inc., 34145 Pacific Coast Highway #504, Dana Point, 92629 California, United States

Funder

Narodowe Centrum Nauki

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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