Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer’s Disease Drug Discovery-Reference-Cited by-同舟云学术

Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer’s Disease Drug Discovery

Published:2020-03-03 Issue:6 Volume:63 Page:3205-3214
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cotrina Ellen Y.¹,Gimeno Ana²^ORCID,Llop Jordi³^ORCID,Jiménez-Barbero Jesús²⁴⁵^ORCID,Quintana Jordi⁶^ORCID,Valencia Gregorio¹,Cardoso Isabel⁷⁸,Prohens Rafel⁹^ORCID,Arsequell Gemma¹^ORCID

Affiliation:

1. Institut de Quı́mica Avançada de Catalunya (I.Q.A.C.-C.S.I.C.), 08034 Barcelona, Spain

2. CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 800, 48160 Derio, Spain

3. CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014 San Sebastian, Spain

4. Ikerbasque, Basque Foundation for Science, Maria Diaz de Haro 13, 48009 Bilbao, Spain

5. Department of Organic Chemistry II, Faculty of Science & Technology, University of the Basque Country, 48940 Leioa, Bizkaia, Spain

6. Research Programme on Biomedical Informatics, Universitat Pompeu Fabra (UPF-IMIM), 08003 Barcelona, Spain

7. IBMC—Instituto de Biologia Molecular e Celular, 4200-135 Porto, Portugal

8. i3S—Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal

9. Unitat de Polimorfisme i Calorimetria, Centres Cientı́fics i Tecnològics, Universitat de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain

Funder

Ministerio de Ciencia, Innovaci?n y Universidades

Ministerio de Econom?a y Competitividad

Instituto de Salud Carlos III

Fundaci? la Marat? de TV3

H2020 European Research Council

Ford-Fundaci?n Apadrina la Ciencia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01970

Reference69 articles.

1. 2019 Alzheimer's disease facts and figures

2. The amyloid hypothesis of Alzheimer's disease at 25 years

3. Why Is Research on Amyloid-β Failing to Give New Drugs for Alzheimer’s Disease?

4. Alzheimer's disease drug development pipeline: 2019

5. Potential Therapeutic Implications of Gelsolin in Alzheimer's Disease

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tetrameric Transthyretin as a Protective Factor Against Alzheimer’s Disease;Molecular Neurobiology;2024-08-27

2. Structure-based virtual screening for the inhibition and clearance of amyloidosis by small molecules as pharmacological chaperones;European Journal of Medicinal Chemistry Reports;2023-12

3. Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics;Proteins: Structure, Function, and Bioinformatics;2023-08-02

4. Anti-amyloid nanoclusters for the treatment of brain hazards associated with incurable neurodegenerative diseases;Materials Today Chemistry;2023-01

5. Binding of common organic UV-filters to the thyroid hormone transport protein transthyretin using in vitro and in silico studies: Potential implications in health.;Environmental Research;2023-01