Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids-Reference-Cited by-同舟云学术

Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids

Published:2019-12-13 Issue:1 Volume:63 Page:433-439
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Obeng Samuel¹²^ORCID,Kamble Shyam H.³⁴,Reeves Morgan E.¹,Restrepo Luis F.¹,Patel Avi¹,Behnke Mira¹,Chear Nelson J.-Y.⁵,Ramanathan Surash⁵,Sharma Abhisheak³⁴,León Francisco²^ORCID,Hiranita Takato¹,Avery Bonnie A.³,McMahon Lance R.¹,McCurdy Christopher R.²⁴

Affiliation:

1. Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States

2. Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States

3. Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States

4. Translational Drug Development Core, Clinical and Translational Sciences Institute, University of Florida, Gainesville, Florida 32610, United States

5. Centre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia

Funder

University of Florida Foundation

National Institute on Drug Abuse

State of Florida

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01465

Reference33 articles.