Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases-Reference-Cited by-同舟云学术

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Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases

Published:2019-08-15 Issue:1 Volume:63 Page:40-51
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Niggenaber Janina¹²^ORCID,Hardick Julia¹²,Lategahn Jonas¹²^ORCID,Rauh Daniel¹²^ORCID

Affiliation:

1. Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227 Dortmund, (Germany)

2. Drug Discovery Hub Dortmund (DDHD) am Zentrum für Integrierte Wirkstoffforschung (ZIW), TU Dortmund University, 44227 Dortmund (Germany)

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00964

Reference97 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

2. Advances in the Development of Molecularly Targeted Agents in Non-Small-Cell Lung Cancer

3. Refining the treatment of NSCLC according to histological and molecular subtypes

4. Epidermal growth factor receptor mutations in lung cancer

5. The EGF receptor family as targets for cancer therapy

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1. Combination of betulinic acid and EGFR-TKIs exerts synergistic anti-tumor effects against wild-type EGFR NSCLC by inducing autophagy-related cell death via EGFR signaling pathway;Respiratory Research;2024-05-20

2. ERBB2 Targeting Reveals a Significant Suppression of Tumorigenesis in Murine Endometrial Cancer with Pten Mutation;Reproductive Sciences;2024-04-18

3. Structural Insights into the Binding Mode of a BLU-945 Analog with Wild-Type and Mutant EGFRs;Journal of Computational Biophysics and Chemistry;2024-03-16

4. Discovery of YK-029A, a novel mutant EGFR inhibitor targeting both T790 M and exon 20 insertion mutations, as a treatment for NSCLC;European Journal of Medicinal Chemistry;2023-10

5. Structural Mechanism and Inhibitors Targeting EGFR Exon 20 Insertion (Ex20ins) Mutations;Journal of Medicinal Chemistry;2023-09-05

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