Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8
Author:
Affiliation:
1. Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, United Kingdom
Funder
Research Councils UK
Wellcome Trust
Cancer Research UK
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b02020
Reference67 articles.
1. Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2. Oncogenic role of the frizzled-7/β-catenin pathway in hepatocellular carcinoma
3. Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Catenin in Breast Cancer Cells
4. Frizzled-8 as a putative therapeutic target in human lung cancer
5. Frizzled 8 promotes the cell proliferation and metastasis of renal cell carcinoma
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Seven-membered N-heterocycles as approved drugs and promising leads in medicinal chemistry as well as the metal-free domino access to their scaffolds;European Journal of Medicinal Chemistry;2024-09
2. Structural insights into Frizzled3 through nanobody modulators;Nature Communications;2024-08-22
3. Progress in the development of modulators targeting Frizzleds;Pharmacological Research;2024-08
4. The emerging understanding of Frizzled receptors;FEBS Letters;2024-05-14
5. Frizzled receptors (FZDs) in Wnt signaling: potential therapeutic targets for human cancers;Acta Pharmacologica Sinica;2024-04-17
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3