Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma
Author:
Affiliation:
1. Celgene Corporation, 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01928
Reference22 articles.
1. American Cancer Society, Cancer Statistic Center Page. https://cancerstatisticscenter.cancer.org/?_ga=2.200904942.1379280727.1580495928-1064148705.1580495928#!/cancer-site/Myeloma (accessed Jan 2020).
2. Current and New Therapeutic Strategies for Relapsed and Refractory Multiple Myeloma: An Update
3. Identification of a Primary Target of Thalidomide Teratogenicity
4. Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
5. The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
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