Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor-Reference-Cited by-同舟云学术

Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor

Published:2019-06-13 Issue:13 Volume:62 Page:6003-6014
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zheng Xiufang¹,Gao Lu¹,Wang Lisha¹,Liang Chungen¹,Wang Baoxia¹,Liu Yongfu¹,Feng Song¹,Zhang Bo¹,Zhou Mingwei¹,Yu Xin¹,Xiang Kunlun¹,Chen Li¹,Guo Tao²^ORCID,Shen Hong C.¹^ORCID,Zou Gang³,Wu Jim Zhen³,Yun Hongying¹^ORCID

Affiliation:

1. Roche Pharma Research and Early Development, Roche Innovation Center Shanghai, Building 5, 720 Cailun Road, Shanghai 201203, China

2. International Discovery Service Unit, Research Service Division, WuXi AppTec (Shanghai) Co., Ltd., Lane 31, Yiwei Road, Waigaoqiao, Shanghai, 200131, China

3. Ark Biosciences Inc., 780 Cailun Road, Suite 701, ZhangJiang Hitech Park, Pudong, Shanghai 201203, China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00654

Reference25 articles.

1. Respiratory Syncytial Virus—A Comprehensive Review

2. Alternative mechanisms for respiratory syncytial virus (RSV) infection and persistence: could RSV be transmitted through the placenta and persist into developing fetal lungs?

3. Respiratory syncytial virus prevention and therapy: Past, present, and future

4. Epidemiologic and Clinical Evidence of a Respiratory Syncytial Virus–Reactive Airway Disease Link

5. Respiratory Syncytial Virus Infection in Elderly and High-Risk Adults

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