Discovery of a Novel Cabazitaxel Nanoparticle–Drug Conjugate (CRLX522) with Improved Pharmacokinetic Properties and Anticancer Effects Using a β-Cyclodextrin–PEG Copolymer Based Delivery Platform-Reference-Cited by-同舟云学术

Discovery of a Novel Cabazitaxel Nanoparticle–Drug Conjugate (CRLX522) with Improved Pharmacokinetic Properties and Anticancer Effects Using a β-Cyclodextrin–PEG Copolymer Based Delivery Platform

Published:2019-10-08 Issue:21 Volume:62 Page:9541-9559
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Metcalf Chester A.¹^ORCID,Svenson Sonke²,Hwang Jungyeon²,Tripathi Snehlata²,Gangal Geeti²,Kabir Sujan²,Lazarus Douglas²,Cole Roderic²,Sweryda-Krawiec Beata²,Shum Pochi²,Brown Donna²,Case Roy I.¹,van der Poll Derek²,Rohde Ellen²,Harlfinger Stephanie¹,Teng Chi-Hse¹,Eliasof Scott²

Affiliation:

1. Novartis Institutes for BioMedical Research Inc., 181 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

2. Cerulean Pharma Inc., 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

Funder

Novartis

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00892

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