Discovery of Thieno[2,3-d]pyrimidine-Based Hydroxamic Acid Derivatives as Bromodomain-Containing Protein 4/Histone Deacetylase Dual Inhibitors Induce Autophagic Cell Death in Colorectal Carcinoma Cells-Reference-Cited by-同舟云学术

Discovery of Thieno[2,3-d]pyrimidine-Based Hydroxamic Acid Derivatives as Bromodomain-Containing Protein 4/Histone Deacetylase Dual Inhibitors Induce Autophagic Cell Death in Colorectal Carcinoma Cells

Published:2020-03-10 Issue:7 Volume:63 Page:3678-3700
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pan Zhaoping¹,Li Xiang¹,Wang Yujia¹,Jiang Qinglin²,Jiang Li²,Zhang Min²,Zhang Nan¹,Wu Fengbo¹,Liu Bo¹,He Gu¹^ORCID

Affiliation:

1. State Key Laboratory of Biotherapy and Department of Urology, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan 610041, PR China

2. School of Pharmacy and Sichuan Province College Key Laboratory of Structure-Specific Small Molecule Drugs, Chengdu Medical College, Chengdu 610500, PR China

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Fundamental Research Funds for the Science & Technology department of Sichuan Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b02178

Reference60 articles.

1. Colorectal cancer statistics, 2017