Discovery and Pharmacological Studies of 4-Hydroxyphenyl-Derived Phosphonium Salts Active in a Mouse Model of Visceral Leishmaniasis-Reference-Cited by-同舟云学术

Discovery and Pharmacological Studies of 4-Hydroxyphenyl-Derived Phosphonium Salts Active in a Mouse Model of Visceral Leishmaniasis

Published:2019-11-08 Issue:23 Volume:62 Page:10664-10675
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Manzano José Ignacio¹,Cueto-Díaz Eduardo J.²^ORCID,Olías-Molero Ana Isabel³,Perea Ana¹,Herraiz Tomás⁴,Torrado Juan J.⁵,Alunda José María³,Gamarro Francisco¹,Dardonville Christophe²^ORCID

Affiliation:

1. Instituto de Parasitología y Biomedicina “López Neyra”, IPBLN−CSIC, Parque Tecnológico de Ciencias de la Salud, 18016 Granada, Spain

2. Instituto de Química Médica, IQM−CSIC, Juan de la Cierva 3, E-28006 Madrid, Spain

3. Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Avda. Puerta de Hierro s/n, 28040 Madrid, Spain

4. Instituto de Ciencia y Tecnología de Alimentos y Nutrición, ICTAN−CSIC, Juan de la Cierva 3, E-28006 Madrid, Spain

5. Departamento de Farmacia Galénica y Tecnología Alimentaria, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza de Ramón y Cajal s/n, 28040 Madrid, Spain

Funder

Ministerio de Ciencia, Innovaci?n y Universidades

Comunidad de Madrid

Secretar?a de Estado de Investigaci?n, Desarrollo e Innovaci?n

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00998

Reference43 articles.

1. WHO Fact-Sheets: Human African Trypanosomiasis. https://www.who.int/en/news-room/fact-sheets/detail/trypanosomiasis-human-african-(sleeping-sickness) (April 12, 2019).

2. WHO. Working to Overcome the Global Impact of Neglected Tropical Diseases: First WHO Report on Neglected Tropical Diseases; World Health Organization: Geneva, 2010.

3. A new chemical series active against African trypanosomes: benzyltriphenylphosphonium salts

4. In search of anti-Trypanosoma cruzi drugs: new leads from a mouse model

5. Testing of drugs for antileishmanial activity in golden hamsters infected with Leishmania donovani

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Antiplatelet activity and toxicity profile of novel phosphonium salts derived from Michael reaction;European Journal of Pharmaceutical Sciences;2024-03

2. Chelation of Mitochondrial Iron as an Antiparasitic Strategy;ACS Infectious Diseases;2024-01-30

3. Antimicrobial potential of quaternary phosphonium salt compounds: a review;Future Medicinal Chemistry;2023-11-06

4. Antimicrobial Conjugated Oligoelectrolytes Containing Triphenylphosphonium Solubilizing Groups;Chemistry – A European Journal;2023-03-06

5. Brønsted acid-mediated tandem cyclization of triarylphosphines and in situ generated ortho-alkynyl quinone methides: access to heterocyclic quaternary phosphonium salts;Chemical Communications;2023