Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer’s Disease Mouse Model-Reference-Cited by-同舟云学术

Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer’s Disease Mouse Model

Published:2019-10-14 Issue:20 Volume:62 Page:9116-9140
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hoffmann Matthias¹,Stiller Carina¹,Endres Erik¹,Scheiner Matthias¹,Gunesch Sandra¹,Sotriffer Christoph¹,Maurice Tangui²,Decker Michael¹^ORCID

Affiliation:

1. Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University Würzburg, Am Hubland, D-97074 Würzburg, Germany

2. INSERM UMR-S1198, University of Montpellier, Place Eugène Bataillon, Montpellier F-34095, France

Funder

Bundesministerium f??r Bildung und Forschung

Deutscher Akademischer Austauschdienst

Campus France

Bayerisches Staatsministerium f??r Bildung und Kultus, Wissenschaft und Kunst

Deutsche Forschungsgemeinschaft

Studienstiftung des Deutschen Volkes

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine