Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase-Reference-Cited by-同舟云学术

Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Published:2019-09-20 Issue:20 Volume:62 Page:9281-9298
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhao Quanju¹,Ren Chaowei,Liu Linyi¹,Chen Jinju,Shao Yubao²,Sun Ning¹,Sun Renhong¹,Kong Ying,Ding Xinyu,Zhang Xianfang,Xu Youwei,Yang Bei,Yin Qianqian,Yang Xiaobao^ORCID,Jiang Biao³

Affiliation:

1. Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China

2. Department of Histology and Embryology, Anhui Medical University, Hefei 230032, China

3. CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

Funder

Natural Science Foundation of Shanghai

China Postdoctoral Science Foundation

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Jing Medicine Technology Ltd.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01264