Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells-Reference-Cited by-同舟云学术

Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells

Published:2020-03-06 Issue:6 Volume:63 Page:3090-3103
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Amato Jussara¹^ORCID,Miglietta Giulia²,Morigi Rita²^ORCID,Iaccarino Nunzia¹,Locatelli Alessandra²,Leoni Alberto²,Novellino Ettore¹^ORCID,Pagano Bruno¹^ORCID,Capranico Giovanni²^ORCID,Randazzo Antonio¹^ORCID

Affiliation:

1. Department of Pharmacy, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy

2. Department of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, 40126 Bologna, Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Fondazione Italiana per la Ricerca sul Cancro

Regione Campania

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01866

Reference53 articles.

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2. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

3. DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential

4. Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression

5. ATRX: Put Me on Repeat

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