How Significant Are Unusual Protein–Ligand Interactions? Insights from Database Mining-Reference-Cited by-同舟云学术

How Significant Are Unusual Protein–Ligand Interactions? Insights from Database Mining

Published:2019-11-15 Issue:22 Volume:62 Page:10441-10455
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kuhn Bernd¹^ORCID,Gilberg Erik¹,Taylor Robin²^ORCID,Cole Jason²^ORCID,Korb Oliver¹

Affiliation:

1. Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, CH-4070 Basel, Switzerland

2. Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01545

Reference65 articles.

1. A Real-World Perspective on Molecular Design

2. It Isn’t, It Is: The C–H···X (X = O, N, F, Cl) Interaction Really Is Significant in Crystal Packing

3. The C–H···Cl hydrogen bond: does it exist?

4. Hydrogen bonds with π-acceptors in proteins: frequencies and role in stabilizing local 3D structures11Edited by R. Huber

5. Strong N−H···π Hydrogen Bonding in Amide−Benzene Interactions

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