Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway-Reference-Cited by-同舟云学术

Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway

Published:2019-04-17 Issue:9 Volume:62 Page:4656-4668
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Karki Rajeshri G.¹^ORCID,Powers James¹,Mainolfi Nello¹,Anderson Karen¹,Belanger David B.¹,Liu Donglei¹,Ji Nan¹,Jendza Keith¹,Gelin Christine F.¹,Mac Sweeney Aengus²,Solovay Catherine¹,Delgado Omar¹,Crowley Maura¹,Liao Sha-Mei¹,Argikar Upendra A.¹^ORCID,Flohr Stefanie²,La Bonte Laura R.¹,Lorthiois Edwige L.²^ORCID,Vulpetti Anna²^ORCID,Brown Ann¹,Long Debby¹,Prentiss Melissa¹,Gradoux Nathalie²,de Erkenez Andrea¹,Cumin Frederic²,Adams Christopher¹^ORCID,Jaffee Bruce¹,Mogi Muneto¹

Affiliation:

1. Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States

2. Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland

Funder

Novartis Institutes for BioMedical Research Inc.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00271

Reference27 articles.