Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies

Published:2019-04-15 Issue:18 Volume:62 Page:8392-8411
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Galperin Ilya¹,Dempwolff Lukas²,Diederich Wibke E.²³,Lauth Matthias¹^ORCID

Affiliation:

1. Center for Tumor and Immune Biology (ZTI), Philipps University Marburg, Hans-Meerwein-Straße 3, 35043 Marburg, Germany

2. School of Pharmacy, Center for Tumor and Immune Biology (ZTI), Philipps University Marburg, Hans-Meerwein-Straße 3, 35043 Marburg, Germany

3. Core Facility Medicinal Chemistry, Philipps University Marburg, Hans-Meerwein-Straße 3, 35043 Marburg, Germany

Funder

Deutsche Forschungsgemeinschaft

Deutsche Krebshilfe

University Hospital Giessen-Marburg

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00188

Reference170 articles.

1. Regulation of Hedgehog Signalling Inside and Outside the Cell

2. Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy

3. Common genetic causes of holoprosencephaly are limited to a small set of evolutionarily conserved driver genes of midline development coordinated by TGF-β, hedgehog, and FGF signaling

4. Patched acts catalytically to suppress the activity of Smoothened

5. Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Blocking smoothened cholesterylation: A strategy for overcoming drug resistance in cancer;Cell Chemical Biology;2024-07

2. Unravelling the Mysteries of the Sonic Hedgehog Pathway in Cancer Stem Cells: Activity, Crosstalk and Regulation;Current Issues in Molecular Biology;2024-05-29

3. Prostate Cancer Stem Cells: Biology and Treatment Implications;International Journal of Molecular Sciences;2023-10-04

4. Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth;Pharmacological Research;2023-09

5. The emerging roles of Hedgehog signaling in tumor immune microenvironment;Frontiers in Oncology;2023-05-05

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3