Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound-Reference-Cited by-同舟云学术

Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound

Published:2014-06-05 Issue:12 Volume:57 Page:5318-5332
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Thomas James B.¹,Giddings Angela M.¹,Wiethe Robert W.¹,Olepu Srinivas¹,Warner Keith R.¹,Sarret Philippe²,Gendron Louis²,Longpre Jean-Michel²,Zhang Yanan¹,Runyon Scott P.¹,Gilmour Brian P.¹

Affiliation:

1. Center for Organic and Medicinal Chemistry, Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States

2. Department of Physiology and Biophysics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Quebec J1H 5N4, Canada

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5003843

Reference63 articles.

1. The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami

2. Diverse Roles of Neurotensin Agonists in the Central Nervous System

3. Occurrence of neurotensinlike immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons