Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles-Reference-Cited by-同舟云学术

Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles

Published:2000-07-01 Issue:15 Volume:43 Page:2797-2804
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Arris Christine E.¹,Boyle F. Thomas¹,Calvert A. Hilary¹,Curtin Nicola J.¹,Endicott Jane A.¹,Garman Elspeth F.¹,Gibson Ashleigh E.¹,Golding Bernard T.¹,Grant Sharon¹,Griffin Roger J.¹,Jewsbury Philip¹,Johnson Louise N.¹,Lawrie Alison M.¹,Newell David R.¹,Noble Martin E. M.¹,Sausville Edward A.¹,Schultz Robert¹,Yu Wyatt¹

Affiliation:

1. Cancer Research Unit and Department of Chemistry, University of Newcastle, Newcastle upon Tyne, NE2 4HH U.K., AstraZeneca Pharmaceuticals, Alderley Park, Cheshire, U.K., Laboratory of Molecular Biophysics and Department of Biochemistry, University of Oxford, Oxford, OX1 3QU U.K., and Developmental Therapeutics Program, National Cancer Institute, Bethesda, Maryland 20892-7458

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990628o

Reference46 articles.

1. Cyclins and cyclin-dependent kinases: a biochemical view

2. Cell cycle control of replication initiation in eukaryotes

3. Cancer Cell Cycles

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