5,5′-Substituted Indirubin-3′-oxime Derivatives as Potent Cyclin-Dependent Kinase Inhibitors with Anticancer Activity-Reference-Cited by-同舟云学术

5,5′-Substituted Indirubin-3′-oxime Derivatives as Potent Cyclin-Dependent Kinase Inhibitors with Anticancer Activity

Published:2010-04-05 Issue:9 Volume:53 Page:3696-3706
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Choi Soo-Jeong¹,Lee Jung-Eun¹,Jeong Soon-Young²,Im Isak¹,Lee So-Deok¹,Lee Eun-Jin³,Lee Sang Kook³,Kwon Seong-Min⁴,Ahn Sang-Gun⁴,Yoon Jung-Hoon⁴,Han Sun-Young⁵,Kim Jae-Il¹²,Kim Yong-Chul¹²

Affiliation:

1. Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of Korea

2. Division of Drug Discovery, Anygen Co., Ltd., Gwangju 500-712, Republic of Korea

3. College of Pharmacy, Ewha Womans University, Seoul 120-759, Republic of Korea

4. Department of Pathology, School of Dentistry, Chosun University, Gwangju 501-759, Republic of Korea

5. Pharmacology Research Center, Korea Research Institute of Chemical Technology, Daejon 305-600, Republic of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100080z

Reference41 articles.

1. Cyclin-Dependent Kinases

2. Principles of CDK regulation

3. The regulation of E2F by pRB-family proteins

4. The retinoblastoma protein and cell cycle control

5. Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

Cited by 87 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Differential Effect of 4H-Benzo[d] [1, 3]oxazines on the Proliferation of Breast Cancer Cell Lines;Current Medicinal Chemistry;2024-11

2. Synthesis of Isatin-derived Heterocycles with Promising Anticancer Activities;Current Topics in Medicinal Chemistry;2024-08-08

3. Bromo-substituted indirubins for inhibition of protein kinase-mediated signalling involved in inflammatory mediator release in human monocytes;Bioorganic Chemistry;2024-08

4. A new 1,2,3-triazole-indirubin hybrid suppresses tumor growth and pulmonary metastasis by mitigating the HGF/c-MET axis in hepatocellular carcinoma;Journal of Advanced Research;2024-08

5. Unlocking therapeutic potential: exploring indole scaffolds and their structural insights as pharmacophores in designing anti-breast cancer agents;Medicinal Chemistry Research;2024-06-12