Concentration and pH Dependent Aggregation of Hydrophobic Drug Molecules and Relevance to Oral Bioavailability-Reference-Cited by-同舟云学术

Concentration and pH Dependent Aggregation of Hydrophobic Drug Molecules and Relevance to Oral Bioavailability

Published:2005-02-26 Issue:6 Volume:48 Page:1974-1983
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Frenkel Yulia Volovik¹,Clark, Arthur D.¹,Das Kalyan¹,Wang Yuh-Hwa¹,Lewi Paul J.¹,Janssen Paul A. J.¹,Arnold Eddy¹

Affiliation:

1. Center for Advanced Biotechnology and Medicine and Department of Chemistry and Chemical Biology, Rutgers University, 679 Hoes Lane, Piscataway, New Jersey 08854, Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry, 675 Hoes Lane, Piscataway, New Jersey 08854, and Center for Molecular Design, Janssen Pharmaceutica NV, Antwerpsesteenweg, 37, B2350 Vosselaar, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049439i

Reference53 articles.

1. A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

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