6-N,N-Dimethylamino-2,3-naphthalimide:  A New Environment-Sensitive Fluorescent Probe in δ- and μ-Selective Opioid Peptides

Author:

Vázquez M. Eugenio1,Blanco Juan B.1,Salvadori Severo1,Trapella Claudio1,Argazzi Roberto1,Bryant Sharon D.1,Jinsmaa Yunden1,Lazarus Lawrence H.1,Negri Lucia1,Giannini Elisa1,Lattanzi Roberta1,Colucci Mariantonella1,Balboni Gianfranco1

Affiliation:

1. Departamento de Química Orgánica y Unidad Asociada al CSIC, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain, Department of Pharmaceutical Sciences and Biotechnology Center, University of Ferrara, I-44100 Ferrara, Italy, Department of Chemistry, University of Ferrara, I-44100 Ferrara, Italy, Medicinal Chemistry Group, Laboratory of Pharmacology and Chemistry, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, Department of Human...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference42 articles.

1. Abbreviations:  in addition to the IUPAC-IUB Commission on Biochemical Nomenclature (J. Biol. Chem.1985,260, 14−42), this article uses the following additional symbols and abbreviations:  Ac, acetyl; Bid, 1H-benzimidazol-2-yl; Boc,tert-butyloxycarbonyl; DAMGO, [d-Ala2,N-Me-Phe4, Gly-ol5] enkephalin; DEL C, deltorphin C, (H-Tyr-d-Ala-Phe-Asp-Val-Val-Gly-NH2); DER, dermorphin (H-Tyr-d-Ala-Phe-Gly-Tyr-Pro-Ser-NH2); DMF,N,N-dimethylformamide; DMSO-d6, hexadeuteriodimethyl sulfoxide; Dmt, 2‘,6‘-dimethyl-l-tyrosine; GPI, guinea-pig ileum; HOBt, 1-hydroxybenzotriazole; HPLC, high performance liquid chromatography; MALDI-TOF, matrix assisted laser desorption ionization time-of-flight; MVD, mouse vas deferens; NMM, 4-methylmorpholine; pA2, negative log of the molar concentration required to double the agonist concentration to achieve the original response; TFA, trifluoroacetic acid; Tic, 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; TIPP, H.Tyr-Tic-Phe-Phe-OH.; TIS, triisopropylsilane; TLC, thin-layer chromatography; TNBS, 2,4,6-trinitrobenzene sulfonic acid; WSC = EDC, 1-ethyl-3-[3‘-dimethyl)aminopropyl]-carbodiimide hydrochloride; Z, benzyloxycarbonyl.

2. Creating new fluorescent probes for cell biology

3. Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors

4. Development and Use of Fluorescent Protein Markers in Living Cells

Cited by 52 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3