A Novel Crystallization Methodology To Ensure Isolation of the Most Stable Crystal Form

Author:

Cote Aaron1,Zhou George1,Stanik Mary1

Affiliation:

1. Global Pharmaceutical Commercialization, P.O. Box 2000, Merck & Co., Rahway, New Jersey 07065, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference15 articles.

1. Growth promotion by H2O in organic solvent—selective isolation of a target polymorph

2. Johnson, B. K.; Tung, H.H.; Lee, I.; Cote, A. S.; Starbuck, C.; Midler, M.Processes and Apparatuses for the Production of Crystalline Organic Microparticle Compositions by Micro-Milling and Crystallization on Micro-Seed and Their Use, U.S. Patent Application 20090087492, 2009.

3. First-principles and direct design approaches for the control of pharmaceutical crystallization

4. Solution Concentration Prediction for Pharmaceutical Crystallization Processes Using Robust Chemometrics and ATR FTIR Spectroscopy

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