The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression
Author:
Affiliation:
1. College of Pharmacy, University of Arizona, Tucson, Arizona 85721, BIO5 Institute, 1657 East Helen Street, Tucson, Arizona 85721, and Arizona Cancer Center, 1515 North Campbell Avenue, Tucson, Arizona 85724
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm900055s
Reference54 articles.
1. Regulation of expression of the c-Myc proto-oncogene
2. Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression
3. The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth
4. Control of c-myc Regulation in Normal and Neoplastic Cells
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