The Selectivity of Austocystin D Arises from Cell-Line-Specific Drug Activation by Cytochrome P450 Enzymes-Reference-Cited by-同舟云学术

The Selectivity of Austocystin D Arises from Cell-Line-Specific Drug Activation by Cytochrome P450 Enzymes

Published:2011-02-24 Issue:4 Volume:74 Page:567-573
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Marks Kevin M.¹,Park Eun Sun¹,Arefolov Alexander¹,Russo Katie¹,Ishihara Keiko¹²,Ring Jennifer E.¹,Clardy Jon³,Clarke Astrid S.¹,Pelish Henry E.¹

Affiliation:

1. Makoto Life Sciences, Inc., 15 DeAngelo Drive, Bedford, Massachusetts 01730, United States

2. Taiho Pharmaceutical Co., LTD., 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan

3. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np100429s

Reference28 articles.

1. Targeting multidrug resistance in cancer

2. Structure of Multidrug-Resistance Proteins of the ATP-Binding Cassette (ABC) Superfamily

3. Anticancer Agents from Unique Natural Products Sources

4. Mutagenic activity of austocystins—Secondary metabolites ofAspergillus ustus

5. Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450

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